The Role of Yamanaka Factors in the Induction of Pluripotent Stem Cells

$19.95

Add to cart
Essay #: 067871
Total text length is 8,845 characters (approximately 6.1 pages).

Excerpts from the Paper

The beginning:
The Role of Yamanaka Factors in the Induction of Pluripotent Stem Cells
In the fall of 2006, Shinya Yamanaka reported a method that turned ordinary body cells into cells more like those of mouse embryonic stem cells (Baker 962). In introducing his method, he wrote that
pluripotent
stem cells multiply rapidly while maintaining their
pluripotency
, or ability to differentiate. Therefore, human embryonic stem cells would be excellent donor sources for cell transplantation therapies, were there not extensive ethical issues as well as the high risk of rejection reactions. “It may be possible to overcome these issues by generating
pluripotent
stem cells directly from a patient’s somatic cells. That somatic cell nuclei acquire an embryonic...
The end:
.....st and Furious.” Nature 458.23 (2009): 962-965.
Kim, Peter Geon and George Q. Daley. “Application of Induced
Pluripotent
Stem Cells to
Hematologic
Disease.”
Cytotherapy
11.8 (2009): 980-989.
Miura, Kyoko, et al. “Variation in the Safety of Induced
Pluripotent
Stem Cell Lines.” Nature Biotechnology 27.8 (2009): 743-745.
Nagata, Shogo, et al. “Efficient Reprogramming of Human and Mouse Primary Extra-Embryonic Cells to
Pluripotent
Stem Cells.” Genes to Cells 14 (2009): 1395-1404.
Pera
, Martin F. and
Kouichi
Hasegawa. “Simpler and Safer Cell Reprogramming.” Nature Biotechnology 26.1 (2008): 59-60.
Yamanaka, Shinya. “Induction of
Pluripotent
Stem Cells from Mouse Fibroblasts by Four Transcription Factors.” Cell Proliferation 41.1 (2008): 51-56.