Critical Evaluation of Evidence Related to the Inverse Association between Dietary Fibre and Risk of Colon Cancer Introduction An overview of literature until 1999 highlights the belief that dietary fibre produces no or minimal effect for reducing the risk of colon cancer. As of the year 2000, the controversy over the value of dietary fibre continues although the outcomes of studies have changed. The most typical of these studies is the European Prospective Investigation of Cancer and Nutrition [EPIC] which was actually a global study involving 519,978 participants. This study demonstrated that changes in dietary habits can contribute to a 40 percent reduction in colorectal cancer across the population (Bingham, 2006). The research...The end:
.....f Nutrition, 96, 803-810. Loo , J. & Clune , Y. (2005). The SYNCAN project. British Journal of Nutrition, 93, S91-S98. Peluso , M. & Airoldi , L. (2008). Bulky DNA adducts, 4-aminobiphenyl-haemoglobin adducts and diet in the European Prospective Investigation into Cancer and Nutrition (EPIC) prospective study. British Journal of Nutrition, 100, 489-495. Pool- Zobel , B. (2005). Insulin–type fructans and reduction in colon cancer risk. British Journal of Nutrition, 93, S73-S90. Qu , H. & Madl , R. (2005). Lignans are involved in the anti-tumor activity of wheat bran in colon cancer. The Journal of Nutrition, 135(3), 598-603. Scott, K. & Duncan, S. (2008). Dietary fibre and the gut microbiota . Nutrition Bulletin, 33, 201-211.