Empirical Antibiotic Monotherapy for Febrile Neutropenia

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Essay #: 061046
Total text length is 6,186 characters (approximately 4.3 pages).

Excerpts from the Paper

The beginning:
Empirical Antibiotic Monotherapy for Febrile Neutropenia
In “Empirical Antibiotic
Monotherapy
for Febrile
Neutropenia
”
Mical
et al explore treatment options for febrile
neutropenia
. They admit the standard treatment for febrile
neutropenia
is a broad-spectrum anti-biotic. However, there are also a number of
monotherapy
options involving B-
lactams
. The authors want to know whether patient outcomes were influenced by the type of B-
lactams
used in
monotherapy
treatments(
Mical
et al, 2006, p.176).
To do this the authors did a systematic review and meta-analysis of randomized controlled trials(
Mical
et al, 2006, p.176). In other words they were doing a literature review of various trials involving the use of B-
lactams
for febrile...
The end:
.....eatment of febrile
neutropenia
(
Mical
et al, 2006, p.176). They also make reasonable recommendations for the use of the remaining B-
lactams
. For example, they don’t eliminate the possibility of using
Cefepime
outright. Instead they suggest that further study is required regarding the use of
Cefepime
(
Mical
et al, 2006, p.176). What conclusions like this they are suggesting that for the time being there are some B-
lactams
that should be used and some that need to be reexamined.
References
Mical
, Paul,
Yahav
,
Dafna
, Fraser, Abigail and Leibovici.2006.
Empirical Antibiotic
Monotherapy
for Febrile
Neutropenia
.
Journal of Antimicrobial Chemotherapy.57: 176-189.
P Value.2010. P Value. Answers.com: http://www.answers.com/
topic/p-value-2.