DNA Damage in Pharmacology and Toxicology Review of a research paper arguing that oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication The following paper looks at an article entitled, “Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.” This paper addresses a number of issues in assessing the article: what was the current state of knowledge prior to the release of the paper? What did the paper describe; how was the work performed; and what was the conclusion of the paper? What impact – or lack of impact – did the paper have upon the field of study; in other words, how did this paper contribute to the present-day state of knowledge or body of knowledge available to...The end:
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